Limbrel's ingredients have GRAS (Generally Recognized As Safe) status according to strict FDA standards. For an ingredient to achieve GRAS status the requirements include a technical demonstration of non-toxicity and safety as well as general recognition and agreement on that safety by experts in the field. Foods for general consumption in the U.S. hold GRAS status and are therefore considered safe for public consumption. Many food additives with widely accepted therapeutic benefits have been approved as GRAS ingredients such as Folic acid, Vitamin C and Calcium.
In human clinical studies, Limbrel has shown safety standards with side effects comparable to placebo. To date, the number of product complaints and adverse events about Limbrel from either physicians or patients has been very low compared to most other prescription products. In animal studies, Limbrel has been shown to be safe with no significant side effects, damage to organs, or changes in organ function at doses up to 20 times the equivalent human dose. In laboratory tests, Limbrel has been shown to be safe with a very low potential for drug interactions.
As with any other prescription product, you should discuss the benefits versus the potential for side effects or allergies with your physician before using Limbrel. No product, including Limbrel, has a 0% chance of ever causing a side effect or adverse reaction.