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Limbrel Overview
Osteoarthritis Symptoms - Knee Osteoarthritis Information

What is Limbrel
Limbrel is the first prescription product developed and formulated specifically to safely meet the distinctive nutritional requirements of patients with osteoarthritis through dual inhibition (COX + LOX) of arachidonic acid metabolization and anti-oxidant action rather than COX-2 selective inhibition. Clinical studies have shown Limbrel to be effective in safely managing the unique nutritional needs of osteoarthritis with side effects comparable to placebo.

Limbrel contains flavocoxid, a proprietary blend of natural ingredients from phytochemical food source materials. Flavocoxid is comprised primarily of the flavonoids such as baicalin and catechin. These or similar ingredients can be found in common foods such as soy, peanuts, cauliflower, kale, apples, apricots, cocoa and green tea. The fact that these and similar ingredients have been widely researched and used in medicinal products in other countries also supports biacalin and catechin’s safety and effectiveness. Limbrel provides levels of these flavonoids needed to meet the distinctive nutritional requirements of people with osteoarthritis and cannot be obtained through simply changing the diet.

Because Limbrel’s ingredients have been derived from natural plant sources, they are not synthetic or artificial. Limbrel is manufactured according to FDA (Food and Drug Administration) current Good Manufacturing Practices (cGMP) for prescription drugs.

FDA regulations require that Limbrel be used only under a physician’s supervision and therefore, it is available by prescription only.


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Limbrel is a prescription medical food product for the clinical dietary management of the metabolic processes of osteoarthritis (OA). Physician supervision required.
Limbrel is not a NSAID, nor a COX-2 selective inhibitor.

U.S. Patent No. 7,108,868 and 7,192,611. Patents pending. | © 2004-2008 Primus Pharmaceuticals, Inc. All rights reserved | Disclaimer | Privacy Policy | Terms of Use
Last updated: May 2008